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Liu Group
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Principles of Genetic Code Expansion
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Applications of Genetic Code Expansion
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Antibody-related Applications of Genetic Code Expansion
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AI Protein Design
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Welcome to Liu Lab !


    Featured Publications
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  1. Cai, W.#, Cui, J.#, Zeng, Z.#, ... , Liu, T.* (2026). Engineering inflammation responsive proteins through nitric oxide caged amino acids. Nature Biomedical Engineering, in press.

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  2. Zeng, Z.#, Chang, L.#, Wang, J.#, ... , Gu, Z.*, Liu, T.* (2026). Controllable-Gene Delivery via Masked Adeno-Associated Viral-Vectors. Nature Materials, in press.

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  3. Wu, X.#, Hu, Y.#, Wang, Q.#, Zhang, W.#, Liu, T.*, Xia, F.*, Lou, X.*, Pu, K.* (2026). Molecular rotor-based probes for protein monitoring in biomedical research. Nature Reviews Chemistry

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  4. Hu, L.#, Cao, W.#, ... , Lou, X.* Liu, T.* (2024). Designing Artificial Fluorescent Proteins and Biosensors by Genetically Encoding Molecular Rotor-based Amino Acids. Nature Chemistry

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  5. Hao, M.#, Ling, X.#, Sun, Y.#, ... , Liu, T.* (2024). Tracking endogenous proteins based on RNA editing-mediated genetic code expansion. Nature Chemical Biology

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  6. Chen, C.#, Yu, G.#, Huang, Y.#, ... , Ye, H.* & Liu, T.* (2021). Genetic-code-expanded cell-based therapy for treating diabetes in mice. Nature Chemical Biology

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  7. Huang, Y.#, Zhang, P.#, Wang, H.#, ... , Liu, T.* Luo, X.*(2024). Genetic Code Expansion: Recent Developments and Emerging Applications. Chemical Reviews

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  8. Wang, Y.#, Zhang, J.#, Han, B.#, ... , Yang, X.* & Liu, T.* (2023). Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates. Nature Communications

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  9. Ling, X., Chang, L., Chen, H., ... , Liu, T.* (2021). Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates. Molecular Cell

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  10. Ling, X., Xie, B., Gao, X., ... , Li, M.*, Liu, T.* (2020). Improving the efficiency of precise genome editing with site-specific Cas9-oligonucleotide conjugates. Science Advances

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